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Midkine

Intervention

1 paper2 findings

MeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 2 countries
  • Funders: American Cancer Society and 5 more
  • Humans1

Outcomes

1

PI3K–AKT signalling

upin rats1

1 study

  1. Midkine activates PI3K–AKT signalling in rats.

    “Midkine treatment of young rats mimics age-related changes via activating PI3K-AKT-SREBF1 pathway”

    Animalsin young rats

    Midkine as a driver of age-related changes and increase in mammary tumorigenesis

    Cancer cell3 Oct 2024

More on PI3K–AKT signalling

Associations

1

Mammary cancer

upin rats1

1 study

  1. Midkine raises the risk of mammary cancer in rats.

    “Midkine treatment of young rats mimics age-related changes via activating PI3K-AKT-SREBF1 pathway and promotes nitroso-N-methylurea-induced mammary tumorigenesis.”

    Animalsnitroso-N-methylurea-treated

    Midkine as a driver of age-related changes and increase in mammary tumorigenesis

    Cancer cell3 Oct 2024

More on Mammary cancer

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