AgingResearch.NewsJoin free

Microsphere injection

Intervention

2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 2 countries
  • Funders: Magyar Tudományos Akadémia and 1 more

Outcomes

2

Gamma-actin expression

downin mice1

1 study

  1. Microsphere injection decreases gamma-actin expression in mice.

    “γ-actin was detected in endothelial cells, but not in pericytes, and decreased in microvessels of microsphere-containing hemispheres.”

    Animalsmicrosphere-containing hemispheres10 μm-size microspherescerebral microvessel

    Expression of alpha smooth muscle actin decreases with ageing and increases upon lumen obstruction in mouse brain pericytes

    GeroScience26 Nov 2024

More on Gamma-actin expression

Alpha smooth muscle actin expression

upin mice1

1 study

  1. Microsphere injection increases alpha smooth muscle actin expression in mice.

    “expression of α-SMA increased significantly in both ensheathing and especially in mesh pericytes”

    Animalsnear microspheres stalled in cerebral capillaries10 μm-size microspheresensheathing and mesh pericytes

    Expression of alpha smooth muscle actin decreases with ageing and increases upon lumen obstruction in mouse brain pericytes

    GeroScience26 Nov 2024

More on Alpha smooth muscle actin expression