Cell Biomaterials
RNA delivery boosts responses in aged human T cells in the lab
In laboratory experiments, delivering several gene-regulating RNAs together enhanced activation and cell-killing responses in aged human T cells.In laboratory experiments, delivering several gene-regulating RNAs together enhanced activation and cell-killing responses in aged human T cells.
Human cell studyBlood and immune system
Who was studiedAged human CD8+ T cells, against inert-miRNA-treated aged human T cells
What changedMultiplexed RNA increased the percentage of IFN-γ-producing aged human T cells by about 20% versus controls
The catchMonitoring ended at day 12; most response gains had diminished by day 8