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Medication intake

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable and 2 more
  • Humans1

Associations

1

Muscle power loss

upin humans1OR 1.87

1 study

  1. Medication intake raises the risk of muscle power loss in humans (OR = 1.87, p = 0.049).

    “Medication intake was associated with an increased risk of decreasing power in women (OR = 1.87, p = 0.049)”

    Humans8 yearsfemalesn = 422

    Changes and major determinants of relative muscle power loss in older adults: results from an 8-year longitudinal study

    European journal of applied physiology15 Oct 2025

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