Maternal protein restriction

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Funders: Conselho Nacional de Desenvolvimento Científico e Tecnológico and 2 more
  • Animals1

Outcomes

3

CD8 expression

upin rats1

1 study
  1. Maternal protein restriction increases CD8 expression in rats.

    “with increased MMP-2 activity, and CD8 expression in the early life, with long-term effects with aging.”

    Animalsmaternal exposure during pregnancy and lactationlungmales

    Impact of maternal protein restriction on the proteomic landscape of male rat lungs across the lifespan

    Molecular and cellular endocrinology31 Aug 2024

More on CD8 expression

MMP-2

upin rats1

1 study
  1. Maternal protein restriction increases MMP-2 in rats.

    “with increased MMP-2 activity, and CD8 expression in the early life, with long-term effects with aging.”

    Animalsmaternal exposure during pregnancy and lactationlungmales

    Impact of maternal protein restriction on the proteomic landscape of male rat lungs across the lifespan

    Molecular and cellular endocrinology31 Aug 2024

More on MMP-2

PI3K–AKT signalling

upin rats1

1 study
  1. Maternal protein restriction activates PI3K–AKT signalling in rats.

    “this outcome is coupled with a rise in the PI3k-AKT-mTOR signaling pathway”

    Animalsmaternal exposure during pregnancy and lactationlungmales

    Impact of maternal protein restriction on the proteomic landscape of male rat lungs across the lifespan

    Molecular and cellular endocrinology31 Aug 2024

More on PI3K–AKT signalling

Associations

1

Immune response

mixedin rats1

1 study
  1. Maternal protein restriction is associated with immune response in rats.

    “Our results demonstrated that MPR lead to structural and immune system pathways changes”

    Animalsmaternal exposure during pregnancy and lactationlungmales

    Impact of maternal protein restriction on the proteomic landscape of male rat lungs across the lifespan

    Molecular and cellular endocrinology31 Aug 2024

More on Immune response

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