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Lymphocytes

Lymphocytes has been studied in 2 papers since 2021: none in people yet, 2 in animals. The research so far is in animals. The newest paper, May 4, 2023: “Inoculation of lymphocytes from young mice prevents progression of age-related hearing loss in a senescence-associated mouse model”.

Intervention

2 papers study it4 findingsUpdated

MeSH

See all 2 papers on lymphocytes

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Mice: a single group. Cells, worms or flies and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Institute on Aging and others
  • Animals2

What did studies of lymphocytes find?

4

Studies of lymphocytes measured 4 outcomes; the most studied are nitric oxide (1 study), spiral ganglion degeneration (1) and auditory threshold (1).

Nitric oxide

downin mice1

1 study

  1. Lymphocytes decrease nitric oxide in mice.

    “avoided spinal ganglion degeneration, cellular immune aging, and nitric oxide production, which causes age-related tissue damage.”

    Animals

    Inoculation of lymphocytes from young mice prevents progression of age-related hearing loss in a senescence-associated mouse model

    Experimental gerontology

More on Nitric oxide

Spiral ganglion degeneration

downin mice1

1 study

  1. Lymphocytes decrease spiral ganglion degeneration in mice.

    “avoided spinal ganglion degeneration, cellular immune aging, and nitric oxide production”

    Animalsspiral ganglion

    Inoculation of lymphocytes from young mice prevents progression of age-related hearing loss in a senescence-associated mouse model

    Experimental gerontology

Auditory threshold

upin mice1

1 study

  1. Lymphocytes improve auditory threshold in a senescence-associated mouse model.

    “Mice that were administered this treatment not only maintained auditory threshold”

    Animalsin a senescence-associated mouse model

    Inoculation of lymphocytes from young mice prevents progression of age-related hearing loss in a senescence-associated mouse model

    Experimental gerontology

Age-related hearing loss

downin mice1

1 study

  1. Lymphocytes prevent age-related hearing loss in mice (at the onset of ARHL).

    “Lymphocytes from young mice inhibited the progression of ARHL.”

    Animalsat the onset of ARHL

    Inoculation of lymphocytes from young mice prevents progression of age-related hearing loss in a senescence-associated mouse model

    Experimental gerontology

More on Age-related hearing loss

Funding

3 grants since 2018

National Institute of Allergy and Infectious Diseases$8.3MNational Institute on Aging$422K

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