Lp(a) lowering

1. Lp(a) lowering lowers the risk of coronary heart disease in silico (26% greater reduction).

   “Lp(a) lowering of 150 nmol/L, 180 nmol/L and 240 nmol/L would result in a 26%, 32% and 84% greater reduction of recurrent CHD events per 1,000 person years”

   In silicoadults with established atherosclerotic cardiovascular diseasen = 20,165

   Estimated absolute coronary heart disease risk reduction with Lp(a) lowering among adults with atherosclerotic cardiovascular disease

   AHA Scientific Sessions 2025 abstract·3 Nov 2025

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