Lonafarnib
Intervention1 paper1 findingPubChem 148195ChEBI 47097
Outcomes
1Lifespan
upin humans1
1 study
Lifespan
upin humans1
Lonafarnib improves lifespan in humans.
Reviewin Hutchinson-Gilford progeria syndrome
Protein farnesylation: from molecular mechanisms to therapeutic targeting in cancer, aging, and beyond · Frontiers in pharmacology · 14 Aug 2026
Latest
2Pharmacological ResearchCells
Extracellular vesicles carrying two microRNAs reduce vascular aging markers in progeria cells
Vesicles from melatonin-treated stem cells targeted SRSF1 and SP1 to lower progerin and cellular prion protein in cell models.Vesicles from melatonin-treated stem cells targeted SRSF1 and SP1 to lower progerin and cellular prion protein in cell models.
Frontiers in PharmacologyReview