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Liver regeneration

Exposure

1 paper2 findings

MeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Japan Society for the Promotion of Science and others
  • Animals1

Outcomes

2

Aging-specific metabolic state

no changein mice1

1 study

  1. Liver regeneration has no effect on aging-specific metabolic state in mice.

    “the aging-specific changes in metabolic state detected in old mouse livers were found to be largely maintained after the completion of liver regeneration.”

    Animalsliverafter completion of liver regeneration

    Differential Effects of Liver Regeneration on Aging-Related Changes in Gene Expression and Metabolic Function

    Aging cell12 Aug 2025

Aging-specific gene expression patterns

downin mice1

1 study

  1. Liver regeneration decreases aging-specific gene expression patterns in mice.

    “the genes with aging-specific expression patterns in old mouse hepatocytes changed to expression levels close to those in young mouse hepatocytes.”

    Animalshepatocyteafter completion of liver regeneration

    Differential Effects of Liver Regeneration on Aging-Related Changes in Gene Expression and Metabolic Function

    Aging cell12 Aug 2025

More on Aging-specific gene expression patterns

Funding

26 grants since 2016

Japan Society for the Promotion of ScienceJP¥109.9mNatural Sciences and Engineering Research Council of CanadaCA$82.5kAgencia Nacional de Investigación y DesarrolloCLP 234.2k

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