Lifestyle activity
Intervention1 paper1 finding
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.
- Humans1
Associations
1Cognitive impairment
downin humans1HR 0.65
1 study
Cognitive impairment
downin humans1HR 0.65
Lifestyle activity lowers the risk of cognitive impairment in humans (HR 0.65, 95% CI 0.45-0.94).
Humans10 yearsn = 8,321
Association Between Combined Multiple Behaviors and Cognitive Impairment in Older Adults: A 10-Year Cohort Study · Preprints.org · 9 Sep 2026 · Preprint