Life events

Exposure

3 papers3 findings

  • 3 independent labs in 2 countries
  • Funders: National Institute on Aging and 3 more
  • Humans3

Outcomes

2

Resilience

downin humans1

1 study
  1. Life events decrease resilience in humans (b = -0.25, p < .001).

    “the decline was greater with a higher number of life events (b=-0.25, p<.001)”

    Humans

    Tracking the Trajectory of Resilience: The Impact of Significant Life Events on Resilience in Older Adults

    GSA 2025 abstractDec 31, 2025

Health-related quality of life

downin humans1

1 study
  1. Life events decrease health-related quality of life in humans.

    “life events negatively predicted HRQoL”

    Humansrural older adults

    The impact of life events on health-related quality of life in rural older adults: the moderating role of social support

    Frontiers in public healthJun 6, 2025

Associations

1

All-cause dementia

upin humans1

1 study
  1. Life events are associated with all-cause dementia in humans (More than 2-fold increase in dementia risk with 3-4 events).

    “When combined, experiencing 3-4 events was associated with a more than 2-fold increase in dementia risk.”

    HumansLife events within the past 2 years3-4 life events16-year follow-upn = 493,787

    Life Events and Incident Dementia: A Prospective Study of 493,787 Individuals Over 16 Years

    The journals of gerontology. Series B, Psychological sciences and social sciencesJun 29, 2024

More on All-cause dementia

Funding

5 grants since 2017

Japan Society for the Promotion of ScienceJP¥9.2mFonds Wetenschappelijk OnderzoekNational Institute on AgingUS$223k

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