Leishmania infantum infection
1 paper3 findings
- 1 lab in 1 country
- Funders: Conselho Nacional de Desenvolvimento Científico e Tecnológico and 1 more
- Humans1
Outcomes
2Cellular senescence
upin humans1
1 study
Cellular senescence
upin humans1
Leishmania infantum infection increases cellular senescence in humans.
“Likewise, senescent (CD57+) and PD1+ CD8+ T cells were higher in asymptomatic HIV/Leish than in AIDS/VL or HIV groups.”
Humansin asymptomatic HIV/Leishmania infantum co-infection compared to HIV alone or AIDS/VL
T-cell activation and senescence in asymptomatic HIV/Leishmania infantum co-infection
PLoS neglected tropical diseases17 Mar 2025
Immune response
upin humans1
1 study
Immune response
upin humans1
Leishmania infantum infection increases immune response in humans.
“activated CD8+CD38+HLA-DR+ T cells were higher in asymptomatic HIV/Leish than HIV”
Humansin asymptomatic HIV/Leishmania infantum co-infection compared to HIV alone
T-cell activation and senescence in asymptomatic HIV/Leishmania infantum co-infection
PLoS neglected tropical diseases17 Mar 2025
Associations
1Visceral leishmaniasis
no changein humans1RR 2.27
1 study
Visceral leishmaniasis
no changein humans1RR 2.27
Leishmania infantum infection is associated with visceral leishmaniasis in humans (RR 2.27, 95% CI 0.920-5.59, p = 0.07).
“The relative risk of developing AIDS/VL was 2.27 (95% CI: 0.920 to 5.59; p = 0.07) to HIV/Leish coinfected subjects with positive leishmania serology compared to HIV subjects without leishmania serology.”
Humansin HIV/Leish coinfected subjects with positive leishmania serology compared to HIV subjects without leishmania serology
T-cell activation and senescence in asymptomatic HIV/Leishmania infantum co-infection
PLoS neglected tropical diseases17 Mar 2025