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Lactococcus cremoris

Intervention

1 paper5 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Japan Society for the Promotion of Science and 1 more
  • 5 of 5 findings with company ties
  • Model organisms1

Outcomes

5

HMOX1

upin mouse cells1

1 study

  1. Lactococcus cremoris increases HMOX1 in mouse cells (>5 times).

    “HO-1 mRNA expression was increased >5 times by inoculation with FC cells.”

    Cells

    Prolonged Lifespan, Improved Perception, and Enhanced Host Defense of Caenorhabditis elegans by Lactococcus cremoris subsp. cremoris

    Microbiology spectrum16 May 2022

More on HMOX1

Advanced glycation end products

downin worms1

1 study

  1. Lactococcus cremoris decreases advanced glycation end products in worms.

    “The increase in autofluorescence from advanced glycation end products (AGEs) with aging was also ameliorated in FC-fed worms.”

    Model organisms

    Prolonged Lifespan, Improved Perception, and Enhanced Host Defense of Caenorhabditis elegans by Lactococcus cremoris subsp. cremoris

    Microbiology spectrum16 May 2022

More on Advanced glycation end products

Chemotaxis index

upin worms1

1 study

  1. Lactococcus cremoris increases chemotaxis index in worms.

    “Further, the chemotaxis index, an indicator of perception ability, was more stable and significantly higher in FC-fed worms than in the control worms.”

    Model organisms

    Prolonged Lifespan, Improved Perception, and Enhanced Host Defense of Caenorhabditis elegans by Lactococcus cremoris subsp. cremoris

    Microbiology spectrum16 May 2022

More on Chemotaxis index

Survival

upin worms1

1 study

  1. Lactococcus cremoris improves survival in worms.

    “The FC-fed worms were tolerant to Salmonella enterica subsp. enterica serovar Enteritidis or Staphylococcus aureus infection and had better survival than the OP50-fed control worms.”

    Model organismsSalmonella enterica or Staphylococcus aureus infection

    Prolonged Lifespan, Improved Perception, and Enhanced Host Defense of Caenorhabditis elegans by Lactococcus cremoris subsp. cremoris

    Microbiology spectrum16 May 2022

Lifespan

upin worms1

1 study

  1. Lactococcus cremoris extends lifespan in worms.

    “Live FC successfully extended the life span and enhanced host defense compared to Escherichia coli OP50 (OP50), a standard food source for C. elegans.”

    Model organisms

    Prolonged Lifespan, Improved Perception, and Enhanced Host Defense of Caenorhabditis elegans by Lactococcus cremoris subsp. cremoris

    Microbiology spectrum16 May 2022

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