Injury

Intervention4 findings

Outcomes

4

Epidermal cell incorporation

upin planarians1Very low certainty

1 study

  1. Injury increases epidermal cell incorporation in planarians.

    Model organismsincluding uninjured regionsepidermisweeks after injury

    Planarian progenitor responses to injury are not specific to missing tissue identity · Development (Cambridge, England) · 29 Sep 2026

Cell incorporation into body-wall muscle

upin planarians1Very low certainty

1 study

  1. Injury induces cell incorporation into body-wall muscle in planarians.

    Model organismsdirect injury; decreased distally and increased at the woundbody-wall muscle

    Planarian progenitor responses to injury are not specific to missing tissue identity · Development (Cambridge, England) · 29 Sep 2026

Cell incorporation into peripheral neurons

upin planarians1Very low certainty

1 study

  1. Injury increases cell incorporation into peripheral neurons in planarians.

    Model organismsdirect injury; spatially imprecise relative to the woundperipheral neurons

    Planarian progenitor responses to injury are not specific to missing tissue identity · Development (Cambridge, England) · 29 Sep 2026

Cell incorporation into brain neurons, ventral nerve cords, and pharynx muscle and neurons

upin planarians1Very low certainty

1 study

  1. Injury increases cell incorporation into brain neurons, ventral nerve cords, and pharynx muscle and neurons in planarians.

    Model organismsproximal injury not affecting the mature tissuebrain neurons, ventral nerve cords, and pharynx muscle and neurons

    Planarian progenitor responses to injury are not specific to missing tissue identity · Development (Cambridge, England) · 29 Sep 2026

Funding

National Institute on AgingUS$81.6kNational Heart, Lung, and Blood InstituteUS$24.7kVeterans Affairs3 grants since 2026

Related