Inguinal subcutaneous white adipose tissue-derived extracellular vesicles

Intervention

1 paper2 findings

  • 1 lab in 2 countries
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

2

Intestinal permeability

downin mice1

1 study
  1. Inguinal subcutaneous white adipose tissue-derived extracellular vesicles decrease intestinal permeability in mice.

    “shifts microbiota composition of aged mice to a "youth" status, which alleviates leaky gut via RA”

    Animalsin aged micesmall intestine

    Subcutaneous white adipose tissue-derived extracellular vesicles maintain intestinal homeostasis via IgA biosynthesis in aging mice

    The Journal of clinical investigation17 Nov 2025

IgA production

upin mice1

1 study
  1. Inguinal subcutaneous white adipose tissue-derived extracellular vesicles improve igA production in mice.

    “Replenishment of "young" iWAT-EVs rejuvenates intestinal IgA production machinery and shifts microbiota composition of aged mice to a "youth" status”

    Animalsin aged micesmall intestine

    Subcutaneous white adipose tissue-derived extracellular vesicles maintain intestinal homeostasis via IgA biosynthesis in aging mice

    The Journal of clinical investigation17 Nov 2025

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