IL-7 receptor blockade

1. IL-7 receptor blockade decreases age-related emphysematous changes.

   “ameliorated age-related emphysematous changes, including restoration of alveolar density.”

   Animalslung

   Dysregulated tissue-resident lymphocytes drive senile emphysema by impairing alveolar regeneration

   bioRxiv (Cold Spring Harbor Laboratory)·26 Apr 2026Preprint

1. IL-7 receptor blockade decreases lung tissue-resident lymphocyte accumulation.

   “In vivo blockade of IL-7 receptor (IL-7R) reduced TRL accumulation in the lungs”

   Animalslung

   Dysregulated tissue-resident lymphocytes drive senile emphysema by impairing alveolar regeneration

   bioRxiv (Cold Spring Harbor Laboratory)·26 Apr 2026Preprint

More on Lung tissue-resident lymphocyte accumulation