Human menstrual blood-derived mesenchymal stromal cells and human umbilical mesenchymal stromal cells

Intervention

1 paper4 findings

  • 1 lab in 2 countries
  • Funder: Fundo para o Desenvolvimento das Ciências e da Tecnologia
  • Animals1

Outcomes

4

Seminiferous tubule fullness and orderly arrangement

upin mice1

1 study
  1. Human menstrual blood-derived mesenchymal stromal cells and human umbilical mesenchymal stromal cells increase seminiferous tubule fullness and orderly arrangement in mice.

    “In the huMenSCs and the huMSCs groups, the testis seminiferous tubules were fuller and more orderly arranged than the negative control group.”

    AnimalsNude mice; comparison with negative controltestis7 months

    Comparative analysis of the bio-safety of HuMSCs and HuMenSCs in the nude mice and their impacts on reproductive organs' histological morphology

    Cell transplantation30 May 2026

Longevity among mice dying during observation

upin mice1

1 study
  1. Human menstrual blood-derived mesenchymal stromal cells and human umbilical mesenchymal stromal cells increase longevity among mice dying during observation in mice.

    “The longevities of the mice died within the observation period of the LXT and the huMSCs groups were significantly longer than that in the other groups”

    AnimalsNude mice that died within the observation period; comparison with other groupsLXT donor-derived huMenSCs or huMSCs7 months

    Comparative analysis of the bio-safety of HuMSCs and HuMenSCs in the nude mice and their impacts on reproductive organs' histological morphology

    Cell transplantation30 May 2026

Visible tumor count

downin mice1

1 study
  1. Human menstrual blood-derived mesenchymal stromal cells and human umbilical mesenchymal stromal cells decrease visible tumor count in mice.

    “The number of visible tumors in the huMenSCs, huMSCs, and the negative control group was lower than that in the positive control group.”

    AnimalsNude mice; comparison with Lewis lung carcinoma cell positive control7 months

    Comparative analysis of the bio-safety of HuMSCs and HuMenSCs in the nude mice and their impacts on reproductive organs' histological morphology

    Cell transplantation30 May 2026

Survival rate

no changein mice1

1 study
  1. Human menstrual blood-derived mesenchymal stromal cells and human umbilical mesenchymal stromal cells have no effect on survival rate in mice.

    “The survival rate was not different among the huMenSCs, the huMSCs, and the negative control (IV injection of PBS) group.”

    AnimalsNude mice; comparison with PBS negative control7 months

    Comparative analysis of the bio-safety of HuMSCs and HuMenSCs in the nude mice and their impacts on reproductive organs' histological morphology

    Cell transplantation30 May 2026

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