Human endothelial progenitor cells

Intervention

1 paper studies it4 findings

Across all fields, 1 paper: none in people yet, 1 in animals

  • 1 lab in 1 country
  • Animals1

Outcomes

4

Embryo development

upin mice1

1 study
  1. Human endothelial progenitor cells improve embryo development in mice.

    “Increased cleavage and blastocyst formation rates and cell numbers in blastocysts from hEPCs-treated aged mice vs. same aged control mice”

    Animalscompared with same aged control micecultured cellsoocyte5 × 104 cells per injection, twicefemales

    Intravenous human endothelial progenitor cell administration into aged mice enhances embryo development and oocyte quality by reducing inflammation, endoplasmic reticulum stress and apoptosis

    The Journal of veterinary medical science

ER unfolded protein response

downin mice1

1 study
  1. Human endothelial progenitor cells decrease ER unfolded protein response in mice.

    “Administration of hEPCs attenuated the level of inflammatory cytokines and adverse apoptotic factor, as well as reducing ER stress in the ovaries.”

    Animalscultured cellsovary5 × 104 cells per injection, twicefemales

    Intravenous human endothelial progenitor cell administration into aged mice enhances embryo development and oocyte quality by reducing inflammation, endoplasmic reticulum stress and apoptosis

    The Journal of veterinary medical science

More on ER unfolded protein response

Adverse apoptotic factor

downin mice1

1 study
  1. Human endothelial progenitor cells decrease adverse apoptotic factor in mice.

    “Administration of hEPCs attenuated the level of inflammatory cytokines and adverse apoptotic factor, as well as reducing ER stress in the ovaries.”

    Animalscultured cellsovary5 × 104 cells per injection, twicefemales

    Intravenous human endothelial progenitor cell administration into aged mice enhances embryo development and oocyte quality by reducing inflammation, endoplasmic reticulum stress and apoptosis

    The Journal of veterinary medical science

More on Adverse apoptotic factor

Inflammatory cytokines

downin mice1

1 study
  1. Human endothelial progenitor cells decrease inflammatory cytokines in mice.

    “Administration of hEPCs attenuated the level of inflammatory cytokines and adverse apoptotic factor, as well as reducing ER stress in the ovaries.”

    Animalscultured cellsovary5 × 104 cells per injection, twicefemales

    Intravenous human endothelial progenitor cell administration into aged mice enhances embryo development and oocyte quality by reducing inflammation, endoplasmic reticulum stress and apoptosis

    The Journal of veterinary medical science

More on Inflammatory cytokines

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