Hookworm exposure

Hookworm exposure has been studied in 2 papers since 2024: 2 observational studies in people. The newest paper, Aug 26, 2025: “Early-life infectious disease exposure, the "hygiene hypothesis," and lifespan: Evidence from hookworm disease”.

Exposure

2 papers study it2 findingsUpdated

“decreasing hookworm exposure is related to improvements in biomarkers for inflammation and skin-tested allergies”
Early-life infectious disease exposure, the "hygiene hypothesis," and lifespan: Evidence from hookworm diseaseProceedings of the National Academy of Sciences of the United States of America2025doi:10.1073/pnas.2504265122
  • 1 lab in 1 country
  • Funders: National Institute of General Medical Sciences and 1 more
  • Humans2

What is Hookworm exposure linked with?

2

Studies link Hookworm exposure with 2 measures, most often skin-tested allergies (1 study) and inflammation biomarkers (1).

Skin-tested allergies

upin humans1

1 study
  1. Hookworm exposure is associated with skin-tested allergies in humans.

    “decreasing hookworm exposure is related to improvements in biomarkers for inflammation and skin-tested allergies”

    HumansReduced hookworm exposure was associated with improvementsSkin

    Early-life infectious disease exposure, the "hygiene hypothesis," and lifespan: Evidence from hookworm disease

    Proceedings of the National Academy of Sciences of the United States of America

More on Skin-tested allergies

Inflammation biomarkers

upin humans1

1 study
  1. Hookworm exposure is associated with inflammation biomarkers in humans.

    “decreasing hookworm exposure is related to improvements in biomarkers for inflammation and skin-tested allergies”

    HumansReduced hookworm exposure was associated with improvements

    Early-life infectious disease exposure, the "hygiene hypothesis," and lifespan: Evidence from hookworm disease

    Proceedings of the National Academy of Sciences of the United States of America

More on Inflammation biomarkers

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