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Homocysteine thiolactone

Intervention

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • Animals1

Outcomes

1

protein aggregation

upin mice1

1 study

  1. Homocysteine thiolactone increases protein aggregation in mice.

    “The N-homocysteinylation of α-synuclein stimulates its aggregation and forms fibrils with enhanced seeding activity and neurotoxicity.”

    Animalsbrain

    N-homocysteinylation of α-synuclein promotes its aggregation and neurotoxicity

    Aging cellNov 27, 2022

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