HMGB1 box a gene therapy
1 paper2 findings
- 1 lab in 1 country
- Funders: National Research Council of Thailand and 2 more
- Animals1
Outcomes
2Weight gain
downin non-human primates1
1 study
Weight gain
downin non-human primates1
HMGB1 box a gene therapy decreases weight gain in non-human primates.
“Box A group trended to gain less weight than the PC group, without experiencing muscle loss.”
Animalsplasmid56 weeksfemales
In vivo (Athens, Greece)Jan 1, 2025
Cortical bone accumulation
upin non-human primates1
1 study
Cortical bone accumulation
upin non-human primates1
HMGB1 box a gene therapy increases cortical bone accumulation in non-human primates.
“Box A promoted cortical bone accumulation in the tibial diaphysis.”
Animalsplasmidbone56 weeksfemales
In vivo (Athens, Greece)Jan 1, 2025
Latest
In Vivo
Long-term Safety Pharmacology and Musculoskeletal Changes of HMGB1 Box A Gene Therapy in Middle-aged Monkeys
Experiments in non-human primatesInterventions