GS967
GS967 has been studied in 1 paper since 2017: none in people yet, 1 in cells. No study of it in people or animals has been published yet. The newest paper, Dec 14, 2017: “Enhanced basal late sodium current appears to underlie the age-related prolongation of action potential duration in guinea pig ventricular myocytes”.
At a glance
The findings reach cells, none yet in people. 1 lab in 1 country.
None of its findings points the other way.
- 1 lab in 1 country
- Funder: Gilead Sciences
- 2 of 2 findings with company ties
- Cells1
What did studies of GS967 find?
2Studies of GS967 measured 2 outcomes; the most studied are early afterdepolarizations (1 study) and action potential duration (1).
Early afterdepolarizations
downin C. porcellus cells1
1 study
Early afterdepolarizations
downin C. porcellus cells1
GS967 decreases early afterdepolarizations in C. porcellus cells (hydrogen peroxide exposure).
“The effect of H2O2 was attenuated by GS967.”
Cellshydrogen peroxide exposureventricular myocyte
Journal of applied physiology (Bethesda, Md. : 1985)
Action potential duration
downin C. porcellus cells1
1 study
Action potential duration
downin C. porcellus cells1
GS967 decreases action potential duration in C. porcellus cells.
“was shortened by the INaL inhibitors GS967 and tetrodotoxin.”
Cellsventricular myocyte
Journal of applied physiology (Bethesda, Md. : 1985)