Gliadin nanoparticles

Gliadin nanoparticles has been studied in 1 paper since 2023: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Aug 2, 2023: “Gliadin nanoparticles for oral administration of bioactives: Ex vivo and in vivo investigations”.

Intervention

1 paper studies it4 findingsUpdated

See all 1 papers on gliadin nanoparticles

At a glance

The findings reach worms or flies, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Worms or flies: a single group. Cells, mice and humans: nothing yet.
  • 1 lab in 1 country
  • Funders: Government of Navarra and 4 more
  • Animals1

What did studies of gliadin nanoparticles find?

4

Studies of gliadin nanoparticles measured 4 outcomes, among them oxidative stress and ROS signaling, lipofuscin and lipid and ceramide metabolism.

Oxidative stress and ROS signaling

no changein worms1

1 study
  1. Gliadin nanoparticles showed no clear effect on oxidative stress and ROS signaling in worms.

    “dihydroethidium staining showed the absence of oxidative stress upon incubation of the worms together with the formulations”

    Model organismsBrij O2-stabilized nanoparticles

    Gliadin nanoparticles for oral administration of bioactives: Ex vivo and in vivo investigations

    International journal of biological macromolecules

More on Oxidative stress and ROS signaling

Lipofuscin

downin worms1

1 study
  1. Gliadin nanoparticles decrease lipofuscin in worms (Dose-dependent decrease).

    “The systems decreased the content of the age-related lipofuscin pigment in the nematodes in a dose-dependent manner, demonstrating a certain antioxidant activity.”

    Model organismsBrij O2-stabilized nanoparticles

    Gliadin nanoparticles for oral administration of bioactives: Ex vivo and in vivo investigations

    International journal of biological macromolecules

More on Lipofuscin

Lipid and ceramide metabolism

no changein worms1

1 study
  1. Gliadin nanoparticles showed no clear effect on lipid and ceramide metabolism in worms.

    “The gliadin nanoparticles influenced neither the egg-laying activity of the worms nor their metabolism of lipids up to 10 μg/mL of nanoformulation.”

    Model organismsBrij O2-stabilized nanoparticlesup to 10 μg/mL

    Gliadin nanoparticles for oral administration of bioactives: Ex vivo and in vivo investigations

    International journal of biological macromolecules

More on Lipid and ceramide metabolism

Egg-laying activity

no changein worms1

1 study
  1. Gliadin nanoparticles showed no clear effect on egg-laying activity in worms.

    “The gliadin nanoparticles influenced neither the egg-laying activity of the worms nor their metabolism of lipids up to 10 μg/mL of nanoformulation.”

    Model organismsBrij O2-stabilized nanoparticlesup to 10 μg/mL

    Gliadin nanoparticles for oral administration of bioactives: Ex vivo and in vivo investigations

    International journal of biological macromolecules

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