Fully hydrogenated canola oil

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Funders: Japan Society for the Promotion of Science and 1 more
  • Animals1

Outcomes

4

Renal dysfunction

downin rats1

1 study
  1. Fully hydrogenated canola oil prevents renal dysfunction in rats.

    “while some rats in the Can group exhibited brain hemorrhaging and renal dysfunction at 16 weeks old, no symptoms were observed in the FHCO group.”

    Animals10 % (w/w)males

    Fully hydrogenated canola oil extends lifespan in stroke-prone spontaneously hypertensive rats

    Lipids in health and disease12 Sep 2021

More on Renal dysfunction

Systolic blood pressure

downin rats1

1 study
  1. Fully hydrogenated canola oil decreases systolic blood pressure in rats.

    “FHCO remarkably decreased the serum cholesterol level compared with Can and the systolic blood pressure from 12 to 16 weeks of age.”

    Animals10 % (w/w)males

    Fully hydrogenated canola oil extends lifespan in stroke-prone spontaneously hypertensive rats

    Lipids in health and disease12 Sep 2021

More on Systolic blood pressure

Body-weight gain

downin rats1

1 study
  1. Fully hydrogenated canola oil decreases body-weight gain in rats (10-12 %).

    “body weight gain in the FHCO group was significantly less (10-12 %) than that in the control group at 9-11 weeks old”

    Animals10 % (w/w)males

    Fully hydrogenated canola oil extends lifespan in stroke-prone spontaneously hypertensive rats

    Lipids in health and disease12 Sep 2021

Lifespan

upin rats1

1 study
  1. Fully hydrogenated canola oil extends lifespan in rats (> 180 days vs 94 ± 3 days).

    “The FHCO (> 180 days) intervention had the greatest effect on lifespan, followed by the Lrd (115 ± 6 days), Plm (101 ± 2 days), and Can (94 ± 3 days) diets.”

    Animalswith 1% NaCl drinking water10 % (w/w)males

    Fully hydrogenated canola oil extends lifespan in stroke-prone spontaneously hypertensive rats

    Lipids in health and disease12 Sep 2021

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