Fraxplus

Fraxplus has been studied in 3 papers since 2024: 1 observational study in people, 2 reviews. The newest paper, Jul 11, 2025: “Effect of FRAXplus adjustments on fracture risk reclassification in older Swedish women-results from the SUPERB-study”.

Exposure

3 papers study it2 findingsUpdated

See all 3 papers on fraxplus

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country.

“The NRI was 4.82% (95% CI: 1.87-7.77%; p < 0.01).”
Effect of FRAXplus adjustments on fracture risk reclassification in older Swedish women-results from the SUPERB-studyOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2025doi:10.1007/s00198-025-07588-w

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 1 lab in 1 country
  • Funders: IngaBritt och Arne Lundbergs Forskningsstiftelse and 3 more
  • 2 of 2 findings with company ties
  • Humans1

What did studies of fraxplus find?

2

Studies of fraxplus measured 2 outcomes; the most studied are major osteoporotic fracture probability (1 study) and Fracture risk prediction (1).

Major osteoporotic fracture probability

upin humans1

1 study
  1. Fraxplus is linked with higher major osteoporotic fracture probability in humans (mean (± SD) change of 4.25% (5.12%)).

    “Overall, 90% (n = 2723) had their 10-year MOF probability adjusted upwards, with a mean (± SD) change of 4.25% (5.12%).”

    Humansfemalesn = 3,028

    Effect of FRAXplus adjustments on fracture risk reclassification in older Swedish women-results from the SUPERB-study

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

More on Major osteoporotic fracture probability

Fracture risk prediction

upin humans1

1 study
  1. Fraxplus is linked with better fracture risk prediction in humans (older Swedish women) (4.82% (95% CI: 1.87-7.77%; p < 0.01)).

    “The NRI was 4.82% (95% CI: 1.87-7.77%; p < 0.01).”

    Humansolder Swedish women8 yearsfemalesn = 3,028

    Effect of FRAXplus adjustments on fracture risk reclassification in older Swedish women-results from the SUPERB-study

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

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