Fractional carbon dioxide laser therapy

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Human trial1

Outcomes

2

Vaginal health

no changein humans1

1 study
  1. Fractional carbon dioxide laser therapy has no effect on vaginal health in humans.

    “vulvovaginal CLT provided no additional benefit for sexual or vaginal health at 12 months.”

    Human trialBreast cancer survivors receiving aromatase inhibitors; sham comparison; both groups received first-line nonhormonal therapyFractional carbon dioxide laserVaginaFive monthly sessions12 monthsn = 67

    Laser Therapy for Sexual Health in Breast Cancer Survivors Receiving Aromatase Inhibitors: A Secondary Analysis of a Randomized Clinical Trial

    JAMA network open1 Oct 2026

Female Sexual Function Index

no changein humans1

1 study
  1. Fractional carbon dioxide laser therapy has no effect on female Sexual Function Index in humans (Between-group difference in change: -0.69 points (95% CI, -3.58 to 2.20)).

    “The CLT group did not differ from the SLT group in FSFI score change from baseline to 12 months”

    Human trialBreast cancer survivors with genitourinary syndrome of menopause and dyspareunia receiving aromatase inhibitors; sham comparison; both groups received first-line nonhormonal therapyFractional carbon dioxide laserVulvovaginal tissueFive monthly sessions12 monthsn = 67

    Laser Therapy for Sexual Health in Breast Cancer Survivors Receiving Aromatase Inhibitors: A Secondary Analysis of a Randomized Clinical Trial

    JAMA network open1 Oct 2026

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