Fortetropin

Fortetropin has been studied in 1 paper since 2020: 1 trial in people. The newest paper, Jul 1, 2020: “Effects of Fortetropin on the Rate of Muscle Protein Synthesis in Older Men and Women: A Randomized, Double-Blinded, Placebo-Controlled Study”.

Intervention

1 paper studies it2 findingsUpdated

MeSH

See all 1 papers on fortetropin

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country.

“The overall magnitude of the difference in muscle protein FSR of Fortetropin from placebo was 18%, with multiple gene ontologies affected.”
Effects of Fortetropin on the Rate of Muscle Protein Synthesis in Older Men and Women: A Randomized, Double-Blinded, Placebo-Controlled StudyThe journals of gerontology. Series A, Biological sciences and medical sciences2020doi:10.1093/gerona/glaa162

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 1 lab in 1 country
  • Human trial1

Studies in people

1 study gave fortetropin to people and measured what changed.

What changedDesignPeopleSource

up: Increases muscle protein fractional synthetic rate18% vs placebo

up: Increases fractional synthetic rate of myofibril, sarcoplasmic and mitochondrial proteins32/38 myofibril, 33/44 sarcoplasmic, 12/17 mitochondrial proteins with higher FSR

Randomized trial21 daysBoth66.4 ± 4.5 yOlder adultsThe journals of gerontology. Series A, Biological sciences and medical sciences, Jul 1, 2020

What did studies of fortetropin find?

2

Studies of fortetropin measured 2 outcomes; the most studied are fractional synthetic rate of myofibril, sarcoplasmic and mitochondrial proteins (1 study) and muscle protein fractional synthetic rate (1).

Fractional synthetic rate of myofibril, sarcoplasmic and mitochondrial proteins

upin humans1

1 study
  1. Fortetropin increases fractional synthetic rate of myofibril, sarcoplasmic and mitochondrial proteins in humans (compared with placebo (cheese powder)) (32/38 myofibril, 33/44 sarcoplasmic, 12/17 mitochondrial proteins with higher FSR).

    “The mean FSR for a majority of proteins in several muscle gene ontologies was higher in the Fortetropin group compared to placebo”

    Human trialcompared with placebo (cheese powder)vastus lateralis19.8 g/d21 days

    Effects of Fortetropin on the Rate of Muscle Protein Synthesis in Older Men and Women: A Randomized, Double-Blinded, Placebo-Controlled Study

    The journals of gerontology. Series A, Biological sciences and medical sciences

More on Fractional synthetic rate of myofibril, sarcoplasmic and mitochondrial proteins

Muscle protein fractional synthetic rate

upin humans1

1 study
  1. Fortetropin increases muscle protein fractional synthetic rate in humans (compared with placebo (cheese powder)) (18% vs placebo).

    “The overall magnitude of the difference in muscle protein FSR of Fortetropin from placebo was 18%, with multiple gene ontologies affected.”

    Human trialcompared with placebo (cheese powder)proteo-lipid complex made from fertilized egg yolkvastus lateralis19.8 g/d21 days

    Effects of Fortetropin on the Rate of Muscle Protein Synthesis in Older Men and Women: A Randomized, Double-Blinded, Placebo-Controlled Study

    The journals of gerontology. Series A, Biological sciences and medical sciences

More on Muscle protein fractional synthetic rate

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