Fontan procedure

1 paper5 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: Canadian Institute for Advanced Research and 1 more

Humans1

Outcomes

C-reactive protein

upin humans1

1 study

Fontan procedure increases C-reactive protein in humans (Cohen's f = 0.62, p < 0.001).
“CRP scores (Cohen's f = 0.62, p < 0.001)”
HumansFontan group vs healthy controls
Epigenetic age acceleration in young adults with congenital heart disease
Clinical epigenetics15 Feb 2026

Latest

1 in 12 months

Clinical Epigenetics16 Feb

Epigenetic age acceleration in young adults with congenital heart disease

Case-control study in peopleGrimAge

Paper

Fontan procedure

Outcomes

Latest

Epigenetic age acceleration in young adults with congenital heart disease

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