Flot regimen
Intervention1 paper1 findingPubChem 56843241
- Humans1
Outcomes
1RAC1, NFE2L2 and mTOR mutations
upin humans1Very low certainty
1 study
RAC1, NFE2L2 and mTOR mutations
upin humans1Very low certainty
Flot regimen increases RAC1, NFE2L2 and mTOR mutations in humans.
Humanspatients undergoing FLOT chemotherapy
Cancer treatment alters mutant selection in normal esophagus · Nature genetics · 11 Sep 2026