RAC1, NFE2L2 and mTOR mutations
Biomarker1 paper1 finding
- Humans1
Interventions
1Flot regimen
upin humans1Very low certainty
1 study
Flot regimen
upin humans1Very low certainty
Flot regimen increases RAC1, NFE2L2 and mTOR mutations in humans.
Humanspatients undergoing FLOT chemotherapy
Cancer treatment alters mutant selection in normal esophagus · Nature genetics · 11 Sep 2026