Estrogens
Intervention1 paper2 findingsPubChem 23676225ChEBI 32143
Outcomes
2Menopause-related quality of life
upin humans1High certainty
1 study
Menopause-related quality of life
upin humans1High certainty
Estrogens improve menopause-related quality of life in humans.
ReviewFemales with vasomotor symptoms; estrogens with or without progestogens or with bazedoxifene.females
Pharmacologic Treatments for Female Menopausal Vasomotor Symptoms: A Systematic Review and Meta-analysis for the American College of Physicians · Annals of internal medicine · 6 Oct 2026
Vasomotor symptom frequency and severity
downin humans1High certainty
1 study
Vasomotor symptom frequency and severity
downin humans1High certainty
Estrogens decrease vasomotor symptom frequency and severity in humans.
ReviewFemales with vasomotor symptoms; estrogens with or without progestogens or with bazedoxifene.females
Pharmacologic Treatments for Female Menopausal Vasomotor Symptoms: A Systematic Review and Meta-analysis for the American College of Physicians · Annals of internal medicine · 6 Oct 2026
Latest
37Osteoporosis therapies affect bone cell spaces differently in mice
In a four-week mouse experiment, a bone-building hormone enlarged the spaces housing bone cells, while a drug that slows bone breakdown stabilised…In a four-week mouse experiment, a bone-building hormone enlarged the spaces housing bone cells, while a drug that slows bone breakdown stabilised their local structure.
New insights into the pathogenesis of osteoporosis and the translational approach to personalized therapy
Use of Vaginal Estrogen in Breast and Gynecologic Cancer Survivors
TRPM3 inhibition reverses depressive behaviors in rats
In ovariectomized rats, inhibiting TRPM3 with naringenin restored serotonin signaling and dendritic arborization while reducing neuroinflammation and…In ovariectomized rats, inhibiting TRPM3 with naringenin restored serotonin signaling and dendritic arborization while reducing neuroinflammation and depressive-like deficits.
Estrogen-responsive variants interact with reproductive risk factors
In 13,026 post-menopausal cases and 108,265 controls, an estrogen-responsive polygenic score interacted with reproductive traits including age at…In 13,026 post-menopausal cases and 108,265 controls, an estrogen-responsive polygenic score interacted with reproductive traits including age at first birth (p=0.0052).