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Estradiol + levonorgestrel

Intervention

1 paper2 findings

PubChemPubChemChEBIChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Institute on Aging
  • Animals1

Outcomes

2

Spatial reference memory

no changein rats1

1 study

  1. Estradiol + levonorgestrel has no effect on spatial reference memory in rats.

    “There were no effects on spatial reference memory.”

    Animalsin middle-aged ovariectomized ratsfemales

    Contrasting effects of individual versus combined estrogen and progestogen regimens as working memory load increases in middle-aged ovariectomized rats: one plus one does not equal two

    Neurobiology of aging7 Dec 2017

Spatial working memory

downin rats1

1 study

  1. Estradiol + levonorgestrel impairs spatial working memory in rats.

    “whereas the E2 + Levo combination impaired high working memory load performance relative to E2 only and Levo only treatments.”

    Animalsrelative to E2 only and Levo only treatmentsfemales

    Contrasting effects of individual versus combined estrogen and progestogen regimens as working memory load increases in middle-aged ovariectomized rats: one plus one does not equal two

    Neurobiology of aging7 Dec 2017

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