Energy insecurity

2 papers5 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

2 independent labs in 1 country

Humans2

Outcomes

Selective Reminding Test score

downin humans1

1 study

Energy insecurity impairs selective Reminding Test score in humans (51 vs. 57, p = 0.059).
“Among women (n = 217), extreme EI was marginally associated with lower average SRT scores than the other EI groups (51 vs. 57, p = 0.059).”
Humansfemalesn = 217
Energy Insecurity and Cognitive Function: A Preliminary Analysis of the Offspring Study
GSA 2025 abstract31 Dec 2025

Vegetable fluency

downin humans1

1 study

Energy insecurity impairs vegetable fluency in humans (10.0 vs 14.0, p = 0.045).
“Among men (n = 101), vegetable fluency was the lowest among those experiencing severe EI compared to those who were energy secure (10.0 vs 14.0, p = 0.045).”
Humansmalesn = 101
Energy Insecurity and Cognitive Function: A Preliminary Analysis of the Offspring Study
GSA 2025 abstract31 Dec 2025

Associations

Stroke

upin humans1OR 1.29

1 study

Energy insecurity is associated with stroke in humans (OR 1.29 (95% CI 0.99-1.69)).
“There was a non-statistically significant higher odds of stroke [1.29 (95% CI 0.99-1.69)].”
Humanslow-income households at and below 200% FPL
Energy Insecurity Associates with Increased Odds of Cardiovascular Disease Risk Factors and Burden: Data from the Behavioral Risk Factor Surveillance System, 2023
AHA Scientific Sessions 2025 abstract3 Nov 2025