Endocarditis donor-derived cardiac mesenchymal stem cell-like cells

1. Endocarditis donor-derived cardiac mesenchymal stem cell-like cells protect against hypoxia/reoxygenation-induced cardiomyocyte injury in human cells.

   “NE-CMSCLCs retained therapeutic potential, as indicated by their ability to protect hypoxia/reoxygenation-injured human cardiomyocytes, albeit less effectively than typical CMSCLCs.”

   CellsProtection was less effective than with typical ischemic donor-derived CMSCLCscardiomyocyte

   Differentiation, Metabolism, and Cardioprotective Secretory Functions of Human Cardiac Stromal Cells from Ischemic and Endocarditis Patients

   Stem cells and development·Jun 28, 2024

1. Endocarditis donor-derived cardiac mesenchymal stem cell-like cells increase osteogenic differentiation in human cells.

   “NE-CMSCLCs had a normal immunophenotype, but exhibited enhanced osteogenic differentiation potential”

   CellsEndocarditis donor cells compared with ischemic donor cellscardiac mesenchymal stem cell-like cells

   Differentiation, Metabolism, and Cardioprotective Secretory Functions of Human Cardiac Stromal Cells from Ischemic and Endocarditis Patients

   Stem cells and development·Jun 28, 2024

1. Endocarditis donor-derived cardiac mesenchymal stem cell-like cells are associated with reactive oxygen species generation in human cells.

   “lower reactive oxygen species generation after oxidative stress compared with typical ischemic CMSCLCs.”

   CellsAfter oxidative stress; endocarditis donor cells compared with ischemic donor cellscardiac mesenchymal stem cell-like cells

   Differentiation, Metabolism, and Cardioprotective Secretory Functions of Human Cardiac Stromal Cells from Ischemic and Endocarditis Patients

   Stem cells and development·Jun 28, 2024

More on Reactive oxygen species generation

1. Endocarditis donor-derived cardiac mesenchymal stem cell-like cells are associated with glycolysis in human cells.

   “reduced glycolysis, and lower reactive oxygen species generation after oxidative stress compared with typical ischemic CMSCLCs.”

   CellsEndocarditis donor cells compared with ischemic donor cellscardiac mesenchymal stem cell-like cells

   Differentiation, Metabolism, and Cardioprotective Secretory Functions of Human Cardiac Stromal Cells from Ischemic and Endocarditis Patients

   Stem cells and development·Jun 28, 2024

More on Glycolysis

1. Endocarditis donor-derived cardiac mesenchymal stem cell-like cells are associated with cellular senescence in human cells.

   “rapid proliferation, reduced senescence, reduced glycolysis, and lower reactive oxygen species generation after oxidative stress compared with typical ischemic CMSCLCs.”

   CellsEndocarditis donor cells compared with ischemic donor cellscardiac mesenchymal stem cell-like cells

   Differentiation, Metabolism, and Cardioprotective Secretory Functions of Human Cardiac Stromal Cells from Ischemic and Endocarditis Patients

   Stem cells and development·Jun 28, 2024

More on Cellular senescence