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EN460

Intervention

1 paper studies it1 finding

PubChemChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Chiang Mai University and 3 more
  • Model organisms1

Outcomes

1

Locomotive functions

upin flies1

1 study

  1. EN460 improves locomotive functions in flies.

    “administration of the chemical probe inhibitor of ERO1A, known as EN460, enhanced locomotive functions and neuromuscular junction (NMJ) morphology in Drosophila UBQLN2ALS model.”

    Model organismsin Drosophila UBQLN2ALS model

    ERO1A inhibition mitigates neuronal ER stress and ameliorates UBQLN2ALS phenotypes in Drosophila melanogaster

    Progress in neurobiology

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