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El niño southern oscillation

Exposure

1 paper2 findings

MeSH D059000

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Canadian Institutes of Health Research and 3 more
  • Humans1

Associations

2

Acute myocardial infarction mortality

upin humans1RR 1.09

1 study

  1. El niño southern oscillation is associated with acute myocardial infarction mortality in humans (RR 1.09, 95% CI 1.04-1.15).

    “increased AMI deaths in western United States (RR 1.09; 95% CI, 1.04-1.15)”

    Humansshift from cool to warm phase of ENSO

    Sea surface temperature variability and ischemic heart disease outcomes among older adults

    Scientific reports9 Feb 2021

Acute myocardial infarction admissions

downin humans1RR 0.89

1 study

  1. El niño southern oscillation is associated with acute myocardial infarction admissions in humans (RR 0.89, 95% CI 0.80-0.99).

    “a shift from cool to warm phase of the El Niño Southern Oscillation (ENSO) was associated with reduced AMI admissions in western Canada (adjusted rate ratio [RR] 0.89; 95% CI, 0.80-0.99)”

    Humansshift from cool to warm phase of ENSO

    Sea surface temperature variability and ischemic heart disease outcomes among older adults

    Scientific reports9 Feb 2021

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