bioRxiv
Young donor immune cells may aid cognition in aged mice
In experiments in aged mice, blocking a receptor for a protein that supports nerve cells impaired cognitive improvements after young donor bone marrow transplants.In experiments in aged mice, blocking a receptor for a protein that supports nerve cells impaired cognitive improvements after young donor bone marrow transplants.
Preprint: mouse studyBlood and immune system
Who was studiedAged mice, one or three months, against transplanted mice without donor-cell depletion
What changedRemoving donor-derived brain immune cells at one month impaired cognitive improvements in aged mice compared with leaving them intact
The catchCognitive effects were assessed only one or three months after transplantation