Domoic acid

  • 1 lab in 1 country
  • Funders: National Institute of Environmental Health Sciences and 3 more
  • Animals1

Outcomes

3

Frailty

upin mice1

1 study
  1. Domoic acid increases frailty in mice.

    “old mice exhibit higher mortality and frailty than young adult mice with the same low-level DA exposures.”

    Animalslow-level domoic acid exposuremultiple weeks

    Low-Level Domoic Acid Exposure Induces Age-like Cardiomyopathy in Young Adult and Aged Mice

    Marine drugs13 Jun 2026

Mortality

upin mice1

1 study
  1. Domoic acid increases mortality in mice.

    “old mice exhibit higher mortality and frailty than young adult mice with the same low-level DA exposures.”

    Animalslow-level domoic acid exposuremultiple weeks

    Low-Level Domoic Acid Exposure Induces Age-like Cardiomyopathy in Young Adult and Aged Mice

    Marine drugs13 Jun 2026

Cardiomyopathy

upin mice1

1 study
  1. Domoic acid induces cardiomyopathy in mice.

    “chronic low-level DA exposure causes irreversible functional cardiomyopathy and protein remodeling in young adult mice that mimics natural cardiac aging.”

    Animalslow-level domoic acid exposuremultiple weeks

    Low-Level Domoic Acid Exposure Induces Age-like Cardiomyopathy in Young Adult and Aged Mice

    Marine drugs13 Jun 2026

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