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DILP5

DILP5 has been studied in 1 paper since 2018: none in people yet, 1 in animals. The research so far is in animals. The newest paper, May 28, 2018: “Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity”.

Intervention

1 paper studies it1 findingUpdated

See all 1 papers on DILP5

At a glance

The findings reach cells, none yet in people. 1 lab in 1 country.

Cells: a single group. Worms or flies, mice and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: American Federation for Aging Research and 3 more
  • 1 of 1 finding with company ties
  • Model organisms1

What did studies of DILP5 find?

1

Studies of DILP5 measured one outcome, Akt.

Akt

upin fly cells1

1 study

  1. DILP5 activates Akt in fly cells (sustained phosphorylation).

    “DILP5 induced sustained phosphorylation of Akt, while DILP2 produced acute, transient Akt phosphorylation.”

    Cellssustained phosphorylation

    Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity

    Frontiers in endocrinology

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