Depletion of gzmk+ t cells

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funders: Foundation for the National Institutes of Health and 1 more
  • Animals1

Outcomes

1

Severe pneumonia

downin mice1

1 study
  1. Depletion of gzmk+ t cells protect against severe pneumonia in mice.

    “mimicked severe pneumonia commonly seen in elderly patients, which was alleviated by depletion of GZMK+ T cells.”

    Animalsin fibroblastic NF-κB activation modellung

    NF-κB-activated fibroblasts orchestrate inflammaging and emergence of pro-inflammatory granzyme K⁺ T cells

    Immunity27 Mar 2026

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