DA3-CH

Intervention

1 paper studies it5 findings

Across all fields, 1 paper: none in people yet, 1 in animals

  • 1 lab in 1 country
  • Animals1

Outcomes

5

AMPK signaling

upin rats1

1 study
  1. DA3-CH activates AMPK signaling in rats.

    “The inactivation of Adenylate activated protein kinase (AMPK)/acetyl CoA carboxylase (ACC) signaling pathway in T2DM rats was promoted by DA3-CH”

    Animalsin T2DM rats

    The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway

    Aging

More on AMPK signaling

Oxidative stress and ROS signaling

downin rats1

1 study
  1. DA3-CH decreases oxidative stress and ROS signaling in rats.

    “reducing blood glucose, blood fat, pancreatic tissue injury, apoptosis, and oxidative stress condition”

    Animalsin T2DM rats

    The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway

    Aging

More on Oxidative stress and ROS signaling

Apoptosis

downin rats1

1 study
  1. DA3-CH decreases apoptosis in rats.

    “reducing blood glucose, blood fat, pancreatic tissue injury, apoptosis, and oxidative stress condition”

    Animalsin T2DM ratspancreas

    The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway

    Aging

More on Apoptosis

Pancreatic tissue injury

downin rats1

1 study
  1. DA3-CH decreases pancreatic tissue injury in rats.

    “reducing blood glucose, blood fat, pancreatic tissue injury, apoptosis, and oxidative stress condition”

    Animalsin T2DM ratspancreas

    The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway

    Aging

Blood glucose

downin rats1

1 study
  1. DA3-CH decreases blood glucose in rats.

    “DA3-CH greatly improved T2DM symptoms by reducing blood glucose, blood fat”

    Animalsin T2DM ratsblood

    The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway

    Aging

More on Blood glucose

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