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Cyclophosphamide + tumor necrosis factor-alpha

Intervention

1 paper1 finding

PubChemPubChemChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Cancer Institute
  • Animals1

Outcomes

1

CD4-CD8+CD44+ thymocytes

upin mice1

1 study

  1. Cyclophosphamide + tumor necrosis factor-alpha increases CD4-CD8+CD44+ thymocytes in mice.

    “Their thymocytes, exposed to X-irradiated EL4, developed anti-EL4 lytic activity and, in comparison with thymocytes of young and age-matched control mice, were markedly enriched in CD4-CD8+CD44+ cells.”

    Animalsthymus

    Thymic anti-tumor effectors in mice cured of lymphoma by cyclophosphamide plus TNF-alpha therapy: phenotypic and functional characterization up to 20 months after initial tumor inoculation

    International journal of cancer18 May 1998

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