CP-2-LPS

1. CP-2-LPS decreases amyloid-beta toxicity in human cells.

   “Biocompatible CP-2 conjugated liposomes (CP-2-LPs) effectively disrupt Aβ aggregation and mitigate Aβ-mediated toxicity in human neuroblastoma cells.”

   Cellsin human neuroblastoma cells

   Multifunctional Liposomes Targeting Amyloid-β Oligomers for Early Diagnosis and Therapy of Alzheimer's Disease

   Small (Weinheim an der Bergstrasse, Germany)·10 Mar 2024

1. CP-2-LPS decreases toxic soluble amyloid β oligomers in worms.

   “In transgenic Caenorhabditis elegans AD models, CP-2-LPs significantly outperformed free CP-2 by improving cognitive and behavioral functions, extending lifespan, and reducing toxic AβO levels.”

   Model organismsin transgenic Caenorhabditis elegans AD models

   Multifunctional Liposomes Targeting Amyloid-β Oligomers for Early Diagnosis and Therapy of Alzheimer's Disease

   Small (Weinheim an der Bergstrasse, Germany)·10 Mar 2024

More on Toxic soluble amyloid β oligomers

1. CP-2-LPS improves cognitive and behavioral functions in worms.

   “In transgenic Caenorhabditis elegans AD models, CP-2-LPs significantly outperformed free CP-2 by improving cognitive and behavioral functions”

   Model organismsin transgenic Caenorhabditis elegans AD models

   Multifunctional Liposomes Targeting Amyloid-β Oligomers for Early Diagnosis and Therapy of Alzheimer's Disease

   Small (Weinheim an der Bergstrasse, Germany)·10 Mar 2024

1. CP-2-LPS extends lifespan in worms.

   “In transgenic Caenorhabditis elegans AD models, CP-2-LPs significantly outperformed free CP-2 by improving cognitive and behavioral functions, extending lifespan, and reducing toxic AβO levels.”

   Model organismsin transgenic Caenorhabditis elegans AD models

   Multifunctional Liposomes Targeting Amyloid-β Oligomers for Early Diagnosis and Therapy of Alzheimer's Disease

   Small (Weinheim an der Bergstrasse, Germany)·10 Mar 2024