Combat exposure

Intervention

4 papers4 findings

  • 3 independent labs in 1 country
  • Funder: Veterans Affairs
  • Human trial1
  • Humans3

Outcomes

2

Mortality

no changein humans1

1 study
  1. Combat exposure has no effect on mortality in humans.

    “While CE did not predict mortality, those who also experienced civilian trauma were 16% more likely to die prematurely.”

    Humansin those who experienced combat exposure

    Forty Years of Stress & Coping Research at the VA Normative Aging Study

    GSA 2025 abstractDec 31, 2025

Cognitive functioning

no changein humans1

1 study
  1. Combat exposure has no effect on cognitive functioning in humans.

    “combat exposure was not associated with any cognitive outcome”

    Humansin male veteransmales

    DOES MILITARY VETERAN STATUS PREDICT COGNITIVE FUNCTIONING IN LATER LIFE?

    GSA 2024 abstractDec 31, 2024

Associations

2

PTSD symptoms

upin humans1

1 study
  1. Combat exposure raises the risk of PTSD symptoms in humans (13 times more likely).

    “WWII Veterans with moderate CE were 13 times more likely to experience PTSD symptoms 45 years later”

    HumansWWII Veterans

    Forty Years of Stress & Coping Research at the VA Normative Aging Study

    GSA 2025 abstractDec 31, 2025

Heart disease

upin humans1

1 study
  1. Combat exposure predicts heart disease in humans (odds ratio = 1.92, 95% confidence interval = 1.13-3.31).

    “combat exposure in Vietnam was a significant predictor (odds ratio = 1.92, 95% confidence interval = 1.13-3.31)”

    Humansin deployed Vietnam veterans 50 years post-War

    Impact of Persistent Combat-Related PTSD on Heart Disease and Chronic Disease Comorbidity in Aging Vietnam Veterans

    Journal of occupational and environmental medicineDec 18, 2024

More on Heart disease

Funding

1 grant since 2022

Veterans Affairs

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