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Cohabitation with non-prematurely aging mice

Exposure

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: European Commission and 1 more
  • Animals1

Outcomes

3

Lifespan

upin mice1

1 study

  1. Cohabitation with non-prematurely aging mice extends lifespan in mice.

    “with most of the parameters in PAM<50% reaching similar values to those in C-ENPAM, and an increased lifespan.”

    Animalsin prematurely aging mice

    The ratio of prematurely aging to non-prematurely aging mice cohabiting, conditions their behavior, immunity and lifespan

    Journal of neuroimmunology10 Apr 2020

Immune response

upin mice1

1 study

  1. Cohabitation with non-prematurely aging mice improves immune response in mice.

    “PAM>50%, PAM = 50% and PAM<50% exhibited better behavioral responses, immunity and redox states in their peritoneal leukocytes than C-PAM.”

    Animalsin prematurely aging miceperitoneal leukocytes2 months

    The ratio of prematurely aging to non-prematurely aging mice cohabiting, conditions their behavior, immunity and lifespan

    Journal of neuroimmunology10 Apr 2020

More on Immune response

Behavior

upin mice1

1 study

  1. Cohabitation with non-prematurely aging mice improves behavior in mice.

    “PAM>50%, PAM = 50% and PAM<50% exhibited better behavioral responses, immunity and redox states in their peritoneal leukocytes than C-PAM.”

    Animalsin prematurely aging mice2 months

    The ratio of prematurely aging to non-prematurely aging mice cohabiting, conditions their behavior, immunity and lifespan

    Journal of neuroimmunology10 Apr 2020

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