Cigarette smoke and heated tobacco product aerosol

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Cells1

Outcomes

2

MMP13 expression

downin human cells1

1 study
  1. Cigarette smoke and heated tobacco product aerosol decreases MMP13 expression in human cells.

    “and decreased that of MMP13, showing changes similar to replicative senescence or DOX-induced senescence.”

    CellsTIG-1 lung fibroblastsHTP at a 10-fold higher concentration than RCrepeated exposure

    Effects of Aerosol Extract From Heated Tobacco Products on Senescence-Associated Gene Expression in Human Lung Fibroblasts

    Geriatrics & gerontology international1 Mar 2026

More on MMP13 expression

CDKN2A, IL1B, MMP1, AHR, CYP1A1, and CYP1B1 expression

upin human cells1

1 study
  1. Cigarette smoke and heated tobacco product aerosol increases CDKN2A, IL1B, MMP1, AHR, CYP1A1, and CYP1B1 expression in human cells.

    “Repeated exposure to RC and HTP (HTP at a 10-fold higher concentration) increased the expression levels of CDKN2A, IL1B, MMP1, AHR, CYP1A1, and CYP1B1,”

    CellsTIG-1 lung fibroblastsHTP at a 10-fold higher concentration than RCrepeated exposure

    Effects of Aerosol Extract From Heated Tobacco Products on Senescence-Associated Gene Expression in Human Lung Fibroblasts

    Geriatrics & gerontology international1 Mar 2026

More on CDKN2A, IL1B, MMP1, AHR, CYP1A1, and CYP1B1 expression

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