Cholesterol-lowering medication

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Humans1

Outcomes

Visual attention

downin humans1

1 study

Cholesterol-lowering medication impairs visual attention in humans (0.393, 95%CI (0.120, 0.665)).
“and a steeper decline of visual attention[0.393,(0.120,0.665)].”
Humansurban population1 yearn = 518
Association between serum lipid dysregulation, management, and cognitive decline in rural and urban Southern Indian population
AAIC 2025 abstract23 Dec 2025

Memory

upin humans1

1 study

Cholesterol-lowering medication improves memory in humans (immediate recall -0.369 (-0.642, -0.097), delayed recall -0.439 (-0.711, -0.166)).
“and memory (immediate [‐0.369,(‐0.642,‐0.097)] and delayed [‐0.439, (‐0.711, ‐0.166)] recall) functioning”
Humansurban population1 yearn = 518
Association between serum lipid dysregulation, management, and cognitive decline in rural and urban Southern Indian population
AAIC 2025 abstract23 Dec 2025

Language function

upin humans1

1 study

Cholesterol-lowering medication improves language function in humans (-0.378, 95%CI (-0.649, -0.106)).
“the use of cholesterol‐lowering medication was associated with a slower decline in language[‐0.378,(‐0.649,‐0.106)]”
Humansurban population1 yearn = 518
Association between serum lipid dysregulation, management, and cognitive decline in rural and urban Southern Indian population
AAIC 2025 abstract23 Dec 2025

Latest

1 in 12 months

AAIC 2025 Abstract23 Dec

Association between serum lipid dysregulation, management, and cognitive decline in rural and urban Southern Indian population

Cohort study of 766 peoplePopulations

Paper

Cholesterol-lowering medication

Outcomes

Latest

Association between serum lipid dysregulation, management, and cognitive decline in rural and urban Southern Indian population

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