Chemically induced neuron transplantation

Chemically induced neuron transplantation has been studied in 1 paper since 2024: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Sep 27, 2024: “Direct conversion of human umbilical cord mesenchymal stem cells into dopaminergic neurons for Parkinson's disease treatment”.

Intervention

1 paper studies it2 findingsUpdated

See all 1 papers on chemically induced neuron transplantation

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Mice: a single group. Cells, worms or flies and humans: nothing yet.
  • 1 lab in 1 country
  • Funders: China Postdoctoral Science Foundation and 1 more
  • Animals1

What did studies of chemically induced neuron transplantation find?

2

Studies of chemically induced neuron transplantation measured 2 outcomes: movement disorders and striatal dopamine.

Movement disorders

downin mice1

1 study
  1. Chemically induced neuron transplantation decreases movement disorders in mice (Parkinson's disease mice).

    “effectively ameliorating movement disorders in PD mice.”

    AnimalsParkinson's disease mice

    Direct conversion of human umbilical cord mesenchymal stem cells into dopaminergic neurons for Parkinson's disease treatment

    Neurobiology of disease

Striatal dopamine

upin mice1

1 study
  1. Chemically induced neuron transplantation increases striatal dopamine in mice (Parkinson's disease mice).

    “CiNs treatment significantly increased the number of tyrosine hydroxylase-positive cells and the concentration of dopamine in the striatum”

    AnimalsParkinson's disease micestriatum

    Direct conversion of human umbilical cord mesenchymal stem cells into dopaminergic neurons for Parkinson's disease treatment

    Neurobiology of disease

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