Cellular reprogramming
Intervention1 paper1 findingMeSH D065150
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.
Funders: National Institute on Aging and 5 more
- Cells1
Outcomes
1Epigenetic age
downin human cells1
1 study
Epigenetic age
downin human cells1
Cellular reprogramming decreases epigenetic age in human cells.
Cellsafter reprogramming of PBMCs to iPSCsn = 99
Characterization of DNA methylation in PBMCs and donor-matched iPSCs shows age-related methylation is reset during stem cell reprogramming · PloS one · 8 Sep 2026
Funding
National Heart, Lung, and Blood InstituteUS$510.5kNational Institute on Deafness and Other Communication DisordersUS$199kNational Institute on AgingUS$79.6k3 grants since 2022
Lymphatic Regeneration by Direct Cellular Reprogramming
National Heart, Lung, and Blood InstituteEmory UniversityUS$510.5k2023–2027
Cellular reprogramming to promote longevity, resilience, and repair in motor unit degeneration
National Institute on AgingHarvard Medical SchoolUS$79.6k2022–2027
Cellular reprogramming of cochlear glial cells to regenerate auditory neurons
National Institute on Deafness and Other Communication DisordersUniversity of Southern CaliforniaUS$199k2024–2029