Cd34+/sox4+ mesenchymal cell transplantation

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: High-level Hospital Construction Project of Guangdong Provincial People's Hospital and 2 more

Animals1

Outcomes

Testosterone

upin mice1

1 study

Cd34+/sox4+ mesenchymal cell transplantation increases testosterone in mice.
“transplanted into LC-disrupted or failure models, Cd34+/Sox4+ cells efficiently colonized the testicular interstitium, resulting in a notable increase in testosterone production.”
Animalstransplanted into LC-disrupted or failure modelstestis
A single-cell atlas of the testicular interstitium defines Leydig progenitor networks sustaining Leydig cell homeostasis across the lifespan
eLife23 Dec 2025

Latest

1 in 12 months

eLife23 Dec

A single-cell atlas of the testicular interstitium defines Leydig progenitor networks sustaining Leydig cell homeostasis across the lifespan

Experiments in miceMechanisms

Paper

Cd34+/sox4+ mesenchymal cell transplantation

Outcomes

Latest

A single-cell atlas of the testicular interstitium defines Leydig progenitor networks sustaining Leydig cell homeostasis across the lifespan

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